Gene description for Pen
Gene name	Pendulin
Gene symbol	Pen
Other names/aliases	2.1 CG4799 DPend Dalpha2 Dimp-alpha2 DmelCG4799 IMPalpha2 Imp alpha-2 Imp alpha2 Imp-alpha2 Impalpha2 Kap alpha2 Kap-alpha2 Kpna2 OHO31 Oho31 Rch1 alpha2 alpha2A-Kap alphaKap2 anon-WO0140519.258 bs29
Species	Drosophila melanogaster
Experiment description of studies that identified Pen in Drosophila S2 cells
1 Experiment ID 471 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23035643    Organism Drosophila melanogaster Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP. Journal name Traffic Publication year 2012 Sample Drosophila S2 cells Sample name Normal-Drosophila S2 tub-Wg Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130023: EV-METRIC:33%, 56%
2 Experiment ID 1278 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22437826    Organism Drosophila melanogaster Experiment description Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Authors Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. Journal name J Biol Chem Publication year 2012 Sample Drosophila S2 cells Sample name S2 cells Isolation/purification methods Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120033: EV-METRIC:33%